Artificial intelligence (AI) is poised to revolutionise healthcare by enabling earlier diagnosis, more personalised treatment, and efficient prevention strategies.

Across Europe, four EU-funded research projects – SmartCHANGE, AI-PROGNOSIS, TRUSTroke, and UMBRELLA – are advancing this transformation through applications in preventive health, neurology, stroke care, and digital platforms.

This white paper synthesises insights from these projects, drawing attention to shared challenges, solutions, and pathways for scaling. Key cross-cutting themes include the trustworthiness and explainability of AI, the need for federated and privacy-preserving data use, and the critical importance of user-centred design. A market study and reflections on strategic positioning conclude the white paper.